History of diseases and its causes

It was Robert Koch,  a physician who first came to know about the disease that was attacking a particular herd of cattle and was destroying them. The farmer first told it to him and he began to search for it. He established a small laboratory in his room and began to investigate. During investigation he found a spiral shaped bacilli. He then wanted to know what kind of disease was it so he injected the disease causing bacteria to a healthy mouse up to many generations. During his search he found that the bacillus were reproducing by forming spores. He developed the rule for the agent that caused the disease. According to the principal first of all the agent should be detected then the strained of it is found and finally it is cultured. The developer or researcher must find the same kind of the bacteria in the newly developed organism.

             Koch went on making his theory and research more and more new by bringing more modernized methods for growing pure cultures of bacteria. He has given a huge break in the modern biology by discovering the cholera bacillus and later it has been proved by the researcher that it is responsible for the cause of tuberculosis. Finally due to his great contribution in on the causes of tuberculosis and in medicine , physiology.
His theory was strongly confirmed when the Pasteur began to work on it and concluded on supporting his theory.  He further  claimed that the animals just got this disease because of they simply worked on the grass. Pasteur later on developed the vaccine against the disease or anthrax.

      In this way it has got a many contribution from different researchers to reach and find the way to culture.